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U.S. Department of Agriculture, Agricultural Research Service’s (ARS) CRISPR Mediated Targeted Mutagenesis

Dept. of Agriculture (USDA)

True fruit flies in the family Tephritidae are destructive agricultural pests invasive to the United States and the subject of many research efforts aimed at its control and eradication. One of the focal points of our research is the development of new genetic sexing strains for use in the sterile insect technique. While developing our methods for inducing desirable phenotypes using non-transgenic approaches for this effort, we created white-eye mutants to demonstrate our ability to apply CRISPR mediated targeted mutagenesis in these non-model systems.

The Agricultural Research Service is the research arm of the USDA. The mission of the Tropical Crop and Commodity Protection Research Unit at the Daniel K. Inouye Pacific Basin Agricultural Research Center is to develop foundational tools to manage pest populations by integrating environmentally compatible strategies that are based on increased understanding of the genome, biology, and ecology of tropical and subtropical fruit flies.

To learn more about the Agricultural Research Service (ARS) - Pacific West Area, visit its FLC Business laboratory profile.

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