Available Technology

A Vaccine for Shigella sonnei for Both Children and Adults

There is currently no vaccine widely available for shigellosis, which affects over 150 million people worldwide and causes over 1 million deaths a year, mostly children. The present invention discloses a novel immunogen to be used in a vaccine for both children and adults. The immunogen, a low-molecular mass O-SP-core fragment, generates high antibody responses in animal studies, which means reduced number of vaccinations. The immunogen is easy to isolate for ease of manufacturing. Additionally, the methods of manufacturing vaccines and protocols of preventing and/or treating Shigellosis had been carried out in the present invention.
Abstract: 
vaccines and diagnostics.
Benefits: 
Vaccine can be used in both children and adults. -Doses of vaccine are reduced. -Immunogen is easy to isolate for easy vaccine production.
applications: 
Inventors: 
John Robbins
Patent Number: 
8,747,863
Internal Laboratory Ref #: 
E-308-2008/0
Lab Representatives
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