Spontaneously Immortalized Avian Cell Line

Spontaneously Immortalized Avian Cell Line

High affinity monoclonal antibodies against Shiga toxin strain Stx2 and hybridomas that produce such antibodies are described. The antibodies may be used in a kit for detecting Stx2 and variants thereof in a sample.

Benefits
• The hybridoma cell lines produce monoclonal antibodies that detect all four variants of Stx2
Immunoassays are rapid, highly specific and sensitive

Applications
• Basis for developing a sensitive immunoassays for detecting variants for Shiga toxin 2
• Immunoassys could be used for monitoring and source-tracking food supplies as well as monitoring contamination of clinical and environmental samples such as feces, soil, air, and water.

Internal Laboratory Ref #: 
87.13
Lab Representatives
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