National Institute of Diabetes and Digestive and Kidney Diseases

FLC Region

Security Lab

No

Address

Building 12A, Room 3011
12 South Drive (MSC 5362)
Bethesda, MD 20892-5632
United States

Laboratory Representative

(P)

301.496.3583

Description

The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) supports a wide range of medical research through grants to universities and other medical research institutions across the country. The Institute also supports government scientists who conduct basic, translational and clinical research across a broad spectrum of research topics and serious, chronic diseases and conditions related to the institute's mission. In addition, the NIDDK supports research training for students and scientists at various stages of their careers and a range of education and outreach programs to bring science-based information to patients and their families, health care professionals and the public.

Mission

The National Institute of Diabetes and Digestive and Kidney Diseases conducts and supports research on many of the most serious diseases affecting public health. The Institute supports much of the clinical research on the diseases of internal medicine and related subspecialty fields as well as many basic science disciplines. The Institute's Division of Intramural Research encompasses the broad spectrum of metabolic diseases such as diabetes, inborn errors of metabolism, endocrine disorders, mineral metabolism, digestive diseases, nutrition, urology and renal disease, and hematology. Basic research studies include biochemistry, nutrition, pathology, histochemistry, chemistry, physical, chemical, and molecular biology, pharmacology, and toxicology. NIDDK extramural research is organized into divisions of program areas:

  • The Division of Diabetes, Endocrinology, and Metabolic Diseases;
  • The Division of Digestive Diseases and Nutrition; and
  • The Division of Kidney, Urologic, and Hematologic Diseases.

The Division of Extramural Activities provides administrative support and overall coordination. A fifth division, the Division of Nutrition Research Coordination, coordinates government nutrition research efforts.

The Institute supports basic and clinical research through investigator-initiated grants, program project and center grants, and career development and training awards. The Institute also supports research and development projects and large-scale clinical trials through contracts.

Technology Disciplines

Technologies
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Capillary Viscometer for Measuring Viscosity of Macromolecular Solutions of Biological Relevance
CDK4-Transformed Mouse Podocytes Useful for Studying Glomerular Diseases
Chromatin Insulator Protecting Expressed Genes of Interest for Human Gene Therapy or Other Mammalian Transgenic Systems
Conditional V2 Vasopressin Receptor Mutant Mice as a Model to Study X-linked Nephrogenic Diabetes Insipidus (XNDI)
Conditionally Immortalized Human Podocyte Cell Lines
Construct for Tetracycline Inducible Podocyte Specific Gene Expression in Mice
Fgfr2 Knockout (Fgfr2tm1Cxd) Mouse Model for Developmental Biology Studies
Fgfr3 Knockout Mouse Model for Developmental Biology Studies
Fgfr4 Knockout Mouse Model for Respiratory System Studies
Generation of Smad3-null Mice and Smad4-conditional Mice

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Facilities
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Laboratory of Biochemistry and Genetics
Laboratory of Biological Modeling
Laboratory of Bioorganic Chemistry
Laboratory of Cell and Molecular Biology
Laboratory of Cellular and Developmental Biology
Laboratory of Chemical Physics
Laboratory of Endocrinology and Receptor Biology
Laboratory of Genetics and Physiology
Laboratory of Molecular Biology
Equipment

No Equipment

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No Funds

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Licenses

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