Available Technology

CONTROLLED VESICLE SELF-ASSEMBLY IN CONTINUOUS TWO PHASE FLOW MICROFLUIDIC CHANNELS

Methods for the formation of liposomes that encapsulate reagents in a continuous 2-phase flow microfluidic network with precision control of size, for example, from 100 nm to 300 micrometer, by manipulation of liquid flow rates are described. By creating a solvent aqueous interfacial region in a microfluidic format that is homogenous and controllable on the length scale of a liposome, fine control of liposome size and polydispersity can be achieved.
Inventors: 
Andreas Jahn, Michael gaitan, Wyatt vreeland, Laurie Locascio
Patent Number: 
9,198,645
Internal Laboratory Ref #: 
04-003US
Lab Representatives
Share to Facebook Share to Twitter Share to Google Plus Share to Linkedin