Available Technology

Isolated Lyssavirus Nucleic Acid and Protein Sequences

A novel strain in the rabies family of viruses, the Shimoni bat virus (SHIBV), has been discovered. Phylogenic and antigenic patterns identify SHIBV as a new species of Lyssavirus. Phylogenic reconstructions of SHIBV and monoclonal antibody typing were used to demonstrate a distinct genetic antigenic pattern. This unique genetic information may be used to create antigens or vaccines against SHIBV and provides opportunity for the development of new diagnostics, therapeutics, and prophylactic therapies for viral infection.
Patent Abstract: 
A novel strain in the rabies family of viruses, the Shimoni bat virus (SHIBV), has been discovered. Phylogenic and antigenic patterns identify SHIBV as a new species of Lyssavirus. Phylogenic reconstructions of SHIBV and monoclonal antibody typing were used to demonstrate a distinct genetic antigenic pattern. This unique genetic information may be used to create antigens or vaccines against SHIBV and provides opportunity for the development of new diagnostics, therapeutics, and prophylactic therapies for viral infection.
Benefits 
Protects against phylogroup II lyssaviruses, unlike current commercially available rabies vaccines -Isolated biomaterials provide novel lyssavirus research tools
applications 
Inventors: 
Ivan Kuzmin
Patent Number: 
PCT/US2011/021309 US Application No. 61/294,988
Internal Laboratory Ref #: 
E-179-2013/0
Share to Facebook Share to Twitter Share to Google Plus Share to Linkedin