To improve safety at nuclear power plants, Dr. Bruce Letellier and his team at Los Alamos National Laboratory (Los Alamos) established a CRADA with the University of Texas to assist South Texas Project Nuclear Operating Company.

The partners developed CASA (Containment Accident Stochastic Analysis) Grande, a software code that automates the evaluation of a single postulated accident so that literally thousands of possible scenarios can be assessed. Los Alamos established an exclusive commercial licensing agreement with Alion Science and Technology Corporation in 2013. This technology addresses the Generic Safety Issue of predicting emergency cooling system failure of nuclear facilities. In the United States alone, there are approximately 104 nuclear facilities.