Through his leadership and vision, Dr. David Swayne has refocused and transformed the Southeast Poultry Research Laboratory (SEPRL) from a general poultry disease research laboratory with national impact and limited technology transfer to an exotic poultry viral disease laboratory with national and international prominence, especially in the area of avian influenza (AI). Dr. Swayne has received several awards for his personal research and is sought by national and international organizations to serve on key policy committees related to research and the use of technology to solve problems. Dr. Swayne has provided technology transfer both through his leadership and his personal research productivity within SEPRL. Examples of major technology transfer include:• Through CRADAs with two companies, Dr. Swayne provided research data on AI vaccines that resulted in the first two fully licensed AI vaccines. One of these vaccines has been manufactured in the U.S. and over 2 billion doses have been exported to Latin America for use in chickens. This vaccine is also designated as part of the USDA AI vaccine bank.• Dr. Swayne developed and transferred research findings that have become the international standard for pasteurization and cooking to kill AI and the Newcastle disease virus in eggs and poultry meat. These data are used by the Food Safety and Inspection Service, the Food and Drug Administration, the World Organization for Animal Health, and the World Health Organization.• Because of his international leadership and re–search productivity on AI, Dr. Swayne is highly sought by veterinary students to do research externships, develop cooperative research agreements with universities and institutions, and sponsor international foreign visitors for train–ing in AI. Dr. Swayne has provided technology transfer and leadership in research outside of SEPRL. He ad–vises leaders in the poultry industries; and state, federal and international action/regulatory agencies on technical and practical matters related to AI, zoonotic infections, biocontainment of exotic pathogens, bioterrorism, and related problems concerning poultry and agriculture.