Greg Failla, Chief Executive Officer of Transpire, Inc., has plenty of reasons to be proud of what the company has accomplished in the past six years. In 2002, Radion Technologies (later reincorporated as Transpire, Inc.) was founded by Failla and two former Los Alamos National Laboratory (LANL) scientists, Drs. John McGhee and Todd Wareing. Drs. McGhee and Wareing launched the startup company while on an entrepreneurial leave of absence from LANL, where they worked as scientists. They were joined soon after by Dr. Allen Barnett, who previously worked as a shielding engineer in the U.S. Navy’s Naval Nuclear Propulsion Program. Through a licensing agreement with LANL, the company built on core technology that originated at the laboratory to develop a complete radiation transport software product, Attila, that can predict how radiation behaves in a broad range of applications faster and more accurately than just about anything else. Since the first official release of Attila in January 2004, interest has grown rapidly. Attila is now being used in over seven countries for applications as diverse as radiation shielding, radiotherapy, medical imaging, fusion research, homeland security, spacecraft design and reactor analysis. In addition, the company has received numerous Small Business Innovation Research grants, including two from the National Cancer Institute for medical imaging and radiotherapy, which total almost $2 million. In 2007, Transpire generated close to $1 million in revenue from software and training alone, and anticipates exceeding this in 2008. Because of these revenues and the large number of grants, Transpire will be able to broaden the software for additional markets. The software has recently been added to the short list of validated codes for International Thermonuclear Experimental Reactor (ITER) neutronics analyses. ITER is a joint international research and development project that aims to demonstrate the scientific and technical feasibility of fusion power and involves partners from all over the world. The company also has a multi-year project with Pacific Northwest National Laboratory to develop a scenario analysis tool to detect radiological threats at U.S. ports of entry. The software has been licensed by leading healthcare companies involved in both radiotherapy and medical imaging. Additionally, Transpire has active collaborations with the University of Texas M.D. Anderson Cancer Center for radiotherapy and Baylor College of Medicine for medical imaging.