Clinical Center at the National Institutes of Health (NIH)

FLC Region

Security Lab



10 Center Drive
RM 6-5551
Bethesda, MD 20892
United States

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Laboratory Representative


The Clinical Center at the National Institutes of Health is the nation's clinical research hospital. Through clinical research, scientific discoveries in the laboratory are translated into new and better medical treatments and therapies. The Clinical Center organization supports programs in the areas of Clinical Research, Patient Care and Hospital Services and Management and Operations.


The NIH Clinical Center is dedicated to improving human health by providing an outstanding environment that facilitates development of diagnostic and therapeutic interventions; training of clinical researchers; and, development of processes to ensure the safe, efficient, and ethical conduct of clinical research. The Clinical Center achieves this mission through a culture that fosters collaboration, innovation, diversity, and the highest ethical standards.

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The Bench-to-Bedside (BtB) Program funds research teams seeking to translate basic scientific findings into therapeutic interventions for patients and to increase understanding of important disease processes.

The BtB Program accomplishes this mission by addressing barriers, such as the traditional silos between basic and clinical researchers in biomedical research, which can hinder progress toward finding new therapeutics for patients in need. BtB teams involve basic and clinical researchers, often from different NIH Institutes and Centers. In 2006, the BtB program's charge was expanded to unite the efforts of intramural and extramural NIH researchers. Intramural science refers to research that takes place on an NIH campus under the auspices of federal employees, while extramural research is funded by NIH and conducted by investigators and institutions outside of NIH.

The BtB program exemplifies the benefits associated with intramural - extramural collaborations; the extramural community gains access to the Clinical Center's unique resources, and the intramural community can pursue innovative research with extramural investigators.

This funding announcement for Opportunities for Collaborative Research at the NIH Clinical Center (U01)is intended to inform extramural (non-NIH) investigators about a mechanism to establish collaborations with NIH intramural investigators and to take advantage of the unique research opportunities available at the NIH Clinical Center. Project budgets are limited to $500,000 a year in direct costs for a period of up to four years, and funds should be designated to support the project-related costs of the extramural principal investigator, the intramural principal investigator / co-investigator, and the Clinical Center.


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