National Institute of Biomedical Imaging and Bioengineering (NIBIB)

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Democracy II, Suite 200
6707 Democracy Boulevard
Bethesda, MD 20892-5477
United States

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The National Institute of Biomedical Imaging and Bioengineering (NIBIB) is an Institute within the National Institutes of Health (NIH) devoted to merging the physical and biological sciences to develop new technologies that improve health. Its goal is to accelerate the pace of discovery and speed the development of biomedical technologies that prevent illnesses or treat them when they do strike. Extraordinary scientific advances are giving us new tools to tackle challenging health problems. Sophisticated imaging techniques allow NIBIB to peer into the human body as never before. Recent developments in bioengineering promise to enhance the body's natural ability to recover from injury and disease. Unlike many other NIH institutes, the NIBIB's mission is not limited to a single disease or group of illnesses; rather it spans the entire spectrum. NIBIB works with doctors from every field of medicine and bring together teams of scientists and engineers from many different backgrounds to develop innovative approaches to health care.


The mission of the National Institute of Biomedical Imaging and Bioengineering (NIBIB) is to improve health by leading the development and accelerating the application of biomedical technologies. The Institute is committed to integrating the physical and engineering sciences with the life sciences to advance basic research and medical care. This is achieved through: research and development of new biomedical imaging and bioengineering techniques and devices to fundamentally improve the detection, treatment, and prevention of disease; enhancing existing imaging and bioengineering modalities; supporting related research in the physical and mathematical sciences; encouraging research and development in multidisciplinary areas; supporting studies to assess the effectiveness and outcomes of new biologics, materials, processes, devices, and procedures; developing technologies for early disease detection and assessment of health status; and developing advanced imaging and engineering techniques for conducting biomedical research at multiple scales. NIBIB extramural research is organized into four divisions:

  • Discovery Science and Technology
  • Applied Science and Technology
  • Inter-Disciplinary Training
  • Program Coordination and Integration

The Institute supports basic research and research training through investigator-initiated grants, contracts, program project and center grants, and career development and training awards.

Technology Disciplines

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Octopod (8-pointed star-shape) Iron Oxide Nanoparticles Enhance MRI T2 Contrast
Resolution Enhancement for Light Sheet Microscopy Systems
Spatial and Temporal Control of Gene Expression Using a Heat Shock Protein Promoter in Combination with Local Heat
Spatially Selective Fixed-Optics Multicolor Fluorescence Detection System For Microfluidic Device
System and Method for Producing Nondiffracting Light Sheets that Improves the Performance of Selective Plane Illumination Microscopy (SPIM)
Two- and Three-Dimensional Autoradiographic Imaging Utilizing Charge Coupled Devices
Ultra-sensitive Diagnostic Detects fg/mL-pg/mL Pathogen/Disease Protein by Visual Color Change


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Laboratory of Cellular Imaging and Macromolecular Biophysics (LCIMB)
Laboratory of Molecular Imaging and Nanomedicine (LOMIN)
Molecular Biomedical Imaging Laboratory (MBIL)
Section on Biophotonics
Section on High Resolution Optical Imaging (HROI)
Trans-NIH Shared Resource on Biomedical Engineering and Physical Science (BEPS)

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The Brain Research through Advancing Innovative Neurotechnologies ® (BRAIN) Initiative is part of a new Presidential focus aimed at revolutionizing our understanding of the human brain. By accelerating the development and application of innovative technologies, researchers will be able to produce a revolutionary new dynamic picture of the brain that, for the first time, shows how individual cells and complex neural circuits interact in both time and space. Long desired by researchers seeking new ways to treat, cure, and even prevent brain disorders, this picture will fill major gaps in our current knowledge and provide unprecedented opportunities for exploring exactly how the brain enables the human body to record, process, utilize, store, and retrieve vast quantities of information, all at the speed of thought.


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