HART mice

Name of License: 
HART mice
By the: 
U.S. Army Medical Research & Development Command - Medical Technology Transfer Office (MTT)
Summary 

Androgen receptor (AR) plays a critical role in prostate cancer. Length of AR’s N-terminal glutamine (Q) tract has been associated with disease risk, and AR somatic mutation may influence disease progression. To study the basis for these effects in an animal model, the mouse AR gene was converted to the human sequence, using homologous recombination in embryonic stem cells.

Tech Name: 
HART mice
Action: 
Intent
Dates: 
Period of time for comments 06/22/2021 - 07/07/2021.
Address: 
1590 Freedman Drive Fort Detrick, MD 21702
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