Lab Spotlight

NIH - Tissue Chips

Vanderbilt NVU Chip Module 1438889598

The tissue chip shown here is one that may improve therapeutic testing in the future.The National Institutes of Health’s National Center for Advancing Translational Sciences, in collaboration with the Defense Advanced Research Projects Agency and the U.S. Food and Drug Administration, is leading the Tissue Chip for Drug Screening program to improve the process of predicting whether drugs will be safe and effective in humans. Through this program, scientists are developing 3-D culture of human-derived cells in bioengineered platforms (or “tissue chips”) that model the structure and function of human organs—such as the lung, liver and heart—and integrating these to mimic complex functions of the human body. Vanderbilt University researchers developed theneurovascular chip,representing the blood-brain-barrier.

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