Available Technology

A New Gene-based Interferon Biotherapeutic

ARS constructed a new type I interferon gene expression system to increase interferon production and antiviral potency. This DNA construct can be inserted into gene-expressing vectors to be used as an antiviral biotherapeutic in pigs. The construct can be modified to be used in other animals.

Benefits
• Uses the most potent porcine interferon gene to increase antiviral activity
• Uses a strong porcine promoter for high gene expression
• Includes another porcine gene to extend the duration of interferon production

Applications
• Use alone for inducing rapid protection against virus infection
• Combine with vaccines for inducing rapid and long-lasting immune protection

Internal Laboratory Ref #: 
115.17
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