Available Technology

Novel Cytochrome P450 Enzymes From Sorghum Bicolor

Two novel cytochrome P450 genes isolated from sorghum, each gene encoding a protein having pentadecatrienyl resorcinol hydroxylase activity. Expression vectors containing these sequences are made and used to elevate levels of pentadecatrienyl resorcinol hydroxylase in transgenic cells and organisms. Divisional patent application. 

Benefits

•  Modification and expression of the sorghum cytochrome P450 enzymes in plant cells could increase sorgoleone levels, or alternatively, introduce its biosynthesis into species lacking the endogenous sorgoleone biosynthetic enzymes

 

Applications

•  Potential use for engineering the production of sorgoleone and related phenolic lipids in crops for enhanced resistance to disease and for the ability to resist weed infestations
 
Patent Number: 
9,926,539 + 9,284,537
Internal Laboratory Ref #: 
145.12 + 41.16
Lab Representatives
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