Available Technology

Phase Sensitive X-ray Imager for More Accurate Digital Mammography for Clinicians

X-Ray mammography based on absorption contrast is currently the primary technique for screening breast cancer. This technique results in high false positives due to the difficulty in distinguishing malignant vs normal soft tissues. A phase sensitive approach can directly measure the phase shift from these tissues, typically orders of magnitude larger than their absorption, thereby reducing false positives.
Patent Abstract: 
This technology uses either of two X-ray wave-front sensor techniques, Hartmann sensing and two-dimensional shear interferometry, both of which are capable of measuring the entire two-dimensional electric field, both the amplitude and the phase, with a single measurement. Capturing both the absorption and phase coefficients of the index of refraction can help to reconstruct the image.
applications 
Internal Laboratory Ref #: 
20909
Lab Representatives
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