Available Technology

Synergistic Combination Agent for Cancer Therapy

The Nanotechnology Characterization Laboratory of the Frederick National Laboratory for Biomedical Research seeks parties interested in collaborative research to co-develop a ceramide and vinca alkaloid combination therapy for treatment of cancer.

Vinca alkaloids alone at therapeutic doses produce the standard side effects of cancer chemotherapy. -The vinca alkaloid-ceramide combination can be administered at lower doses with comparable efficacy and may allow for more frequent dosing (metronomic dosing). -The novel mechanism of action of this combination appears to be selective to cancer cells.

Stephan Stern

Lab Representatives
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